Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.48 |
| ▸ | MMP13 | P45452 | 11/20 | 0.48 |
| ▸ | MMP9 | P14780 | 11/20 | 0.48 |
| ▸ | MMP1 | P03956 | 10/20 | 0.48 |
| ▸ | MMP3 | P08254 | 10/20 | 0.48 |
| ▸ | MMP7 | P09237 | 9/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240400 | 1.00 | MMP2 (0.48) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL28005180 | 0.82 | ALDH1A1 (0.46) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL20906397 | 0.82 | ALDH1A1 (0.46) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL20906396 | 0.82 | ALDH1A1 (0.46) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL20906595 | 0.79 | CA2 (0.43) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL20906594 | 0.79 | CA2 (0.43) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL24425135 | 0.77 | CA14 (0.44) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL24425137 | 0.77 | CA14 (0.44) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL5839741 | 0.74 | KDM4E (0.49) | MMP2MMP13MMP9MMP1MMP3 | |
| SCHEMBL29612792 | 0.74 | KDM4E (0.49) | MMP2MMP13MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099424-A1 | Nitrile-Containing Antiviral Compounds | PFIZER INC. (US) | 2025-03-27 | — | — | US | disclosed |
| CN-114681443-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2024-05-10 | — | — | CN | disclosed |
| CN-116789648-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-09-22 | — | — | CN | disclosed |
| CN-114466838-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-05-02 | — | — | CN | disclosed |
| CN-114681443-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-07-01 | — | — | CN | disclosed |
| CN-114466838-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-05-10 | — | — | CN | disclosed |
| CN-107429047-B | Polyester resin composition and method for producing same | 东丽株式会社 | 2020-01-21 | — | — | CN | disclosed |
| CN-104326949-B | A kind of alternative functionalized ion liquid of amino acid separation, preparation method and application thereof | 浙江工商大学 | 2016-07-27 | — | — | CN | disclosed |
| CN-104326949-A | Functionalized ionic liquid capable of selectively separating amino acids, preparation method and application thereof | UNIV ZHEJIANG GONGSHANG | 2015-02-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099424-A1 | Nitrile-Containing Antiviral Compounds | ACE2, NOS2, EIF2AK2 | MMP2 1588/4885MMP13 3458/4885MMP9 1272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.