Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307940 | 0.93 | MAPT (0.63) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL7353785 | 0.86 | HSD17B10 (0.62) | MAPTALDH1A1KCNJ1LMNAPKM | |
| Methane SCHEMBL16579836 | 0.85 | MAPT (0.51) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL28289713 | 0.85 | ALDH1A1 (0.65) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL28307941 | 0.84 | KDM4E (0.68) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL28005156 | 0.84 | MAPT (0.62) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL7608604 | 0.82 | KDM4E (0.67) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL9642123 | 0.82 | MAPT (0.78) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL7350400 | 0.82 | KDM4E (0.54) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL7033532 | 0.81 | MAPT (0.72) | MAPTALDH1A1KCNJ1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418806-B | A kind of Preparation Method And Their Intermediate of hydrochloric acid N- demethyl bendamustine | 上海龙翔生物医药开发有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-104418806-A | Preparation method of hydrochloric acid N-demethylated bendamustine and intermediate of hydrochloric acid N-demethylated bendamustine | KNOWSHINE SHANGHAI PHARMACHEMICALS INC | 2015-03-18 | — | — | CN | disclosed |