Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350393 | 0.91 | KDM4E (0.67) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL28307940 | 0.88 | MAPT (0.63) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL28289712 | 0.87 | KDM4E (0.51) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL28289753 | 0.85 | CHRM1 (0.58) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL28289713 | 0.85 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL28005154 | 0.82 | MAPT (0.55) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL8601352 | 0.81 | KDM4E (0.80) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL7867650 | 0.81 | PKM (0.67) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL9642123 | 0.81 | MAPT (0.78) | KDM4EMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL28005156 | 0.81 | MAPT (0.62) | KDM4EMAPTALDH1A1KCNJ1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988794-B | Method for synthesizing nitrobenzimidazole derivatives through enzyme catalysis in continuous flow reactor | 浙江农林大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-109988794-A | A method of the Enzyme catalyzed synthesis nitrobenzimidazole analog derivative in continuous flow reactor | 浙江农林大学 | 2019-07-09 | — | — | CN | disclosed |
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0672034-A4 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION. | SMITHKLINE BEECHAM CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0672034-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |