Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005196 | 0.81 | TUBB4A (0.49) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4057561 | 0.72 | ADORA3 (1.00) | ADORA3ADORA2BMAPTALDH1A1KDM4E | |
| SCHEMBL9548033 | 0.71 | MAPT (0.69) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9548102 | 0.71 | MAPT (0.69) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7786558 | 0.70 | TUBB1 (0.83) | L3MBTL1 | |
| SCHEMBL1303254 | 0.70 | SMN1; SMN2 (0.61) | ADORA3MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6546252 | 0.69 | MAPT (0.66) | ADORA3ADORA2BMAPTALDH1A1KDM4E | |
| SCHEMBL6426146 | 0.69 | TUBB4A (0.78) | MAPTALDH1A1KDM4ELMNACSNK1D | |
| SCHEMBL1304286 | 0.69 | PLTP (0.62) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL1304135 | 0.68 | MAPT (0.53) | ADORA3MAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418821-A | 2, 4-substituted 5- (3,4, 5-trimethoxyphenyl) thiazole derivative and preparation method and application thereof | WEST CHINA HOSPITAL SICHUAN UNIV | 2015-03-18 | — | — | CN | claimed |
| CN-104418821-A | 2, 4-substituted 5- (3,4, 5-trimethoxyphenyl) thiazole derivative and preparation method and application thereof | WEST CHINA HOSPITAL SICHUAN UNIV | 2015-03-18 | — | — | CN | disclosed |