Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950152 | 0.76 | ALOX5 (0.59) | ALOX5NQO2TRPM4KDM4EMEN1 | |
| SCHEMBL27626882 | 0.74 | ESR1 (0.47) | ALOX5KDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL841559 | 0.72 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2GAACYP2C19 | |
| SCHEMBL3819839 | 0.72 | SRC (0.37) | CYP1A2HTR2ACYP2A6 | |
| SCHEMBL8047307 | 0.72 | GABRA1 (0.40) | CYP1A2HPGDHIF1A | |
| SCHEMBL1505828 | 0.71 | ALOX5 (0.55) | ALOX5GPR84NQO2KDM4EMEN1 | |
| SCHEMBL28926401 | 0.70 | TTR (0.35) | — | |
| SCHEMBL300507 | 0.69 | ALOX5 (0.57) | ALOX5GPR84NQO2KDM4EMEN1 | |
| SCHEMBL29362847 | 0.69 | ALOX5 (0.57) | ALOX5GPR84NQO2KDM4EMEN1 | |
| SCHEMBL13433266 | 0.69 | ALOX5 (0.52) | ALOX5GPR84NQO2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088828-A | Chiral fluorene containing 9-quaternary carbon stereogenic center and preparation method thereof | 常州大学 | 2023-11-21 | — | — | CN | claimed |
| CN-104610363-A | Phosphoramidite ligand as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-05-13 | — | — | CN | claimed |
| CN-117088828-A | Chiral fluorene containing 9-quaternary carbon stereogenic center and preparation method thereof | 常州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-104610363-A | Phosphoramidite ligand as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-05-13 | — | — | CN | disclosed |