Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 9/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1926049 | 0.81 | ELANE (0.34) | ELANECA2 | |
| SCHEMBL10443000 | 0.72 | — | — | |
| SCHEMBL17787029 | 0.72 | ELANE (0.33) | ELANE | |
| SCHEMBL30027475 | 0.71 | ELANE (0.36) | ELANE | |
| SCHEMBL9707265 | 0.70 | ELANE (0.32) | ELANECA2 | |
| SCHEMBL7761698 | 0.70 | L3MBTL1 (0.36) | ELANECA2CA1CA9CA12 | |
| SCHEMBL9294567 | 0.70 | ELANE (0.32) | ELANECA2CA9 | |
| SCHEMBL28049369 | 0.69 | — | — | |
| SCHEMBL28001050 | 0.67 | ELANE (0.33) | ELANE | |
| SCHEMBL28214062 | 0.65 | PRKCA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461326-A | Novel substituted N' -hydroxycarbamimidoyl-1, 2, 5-oxadiazole compounds as indoleamine 2, 3-dioxygenase (IDO) inhibitors | MERCK SHARP & DOHME | 2019-11-15 | — | — | CN | disclosed |
| CN-105792821-B | Therapeutic and/or prophylactic agent for pain comprising 1-indansulfamide derivative | 卫材R&D管理有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-104797555-B | N-substituted benzamides and methods of use thereof | 基因泰克公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107108593-A | Substituted oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II | 美迪福伦DBT有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107074829-A | For suppressing Microsomal prostaglandin E2The new methyl piperidine compound of synthetase 1 | 伊莱利利公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104395285-B | Indanesulfonamide derivatives | Sanitary Material R&D Management Co.,Ltd. (JP) | 2016-04-13 | — | — | CN | disclosed |
| CN-104797555-A | N-substituted benzamides and methods of use thereof | GENENTECH INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104395285-A | Novel indanesulfonamide derivatives | EISAI R&D MAN CO LTD | 2015-03-04 | — | — | CN | disclosed |