Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787029 | 0.81 | ELANE (0.33) | ELANEDGAT1 | |
| SCHEMBL9294567 | 0.79 | ELANE (0.32) | ELANEDGAT1CA2CA9CYP1A2 | |
| SCHEMBL28183441 | 0.79 | ALDH1A1 (0.38) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL9707265 | 0.79 | ELANE (0.32) | ELANEDGAT1CA2 | |
| SCHEMBL10443000 | 0.76 | — | — | |
| SCHEMBL9707335 | 0.75 | TDP1 (0.33) | L3MBTL1 | |
| SCHEMBL30027475 | 0.75 | ELANE (0.36) | ELANEDGAT1 | |
| SCHEMBL1949138 | 0.73 | DGAT1 (0.41) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL8255036 | 0.72 | — | — | |
| SCHEMBL28049369 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753519-B | Diacylated hydroxylamine derivatives | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-08-05 | — | — | CN | claimed |
| CN-105130855-B | Succinylated hydroxy amine derivatives and application thereof | 约翰斯霍普金斯大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-105130855-A | Bis-Acylated Hydroxylamine Derivatives | UNIV JOHNS HOPKINS | 2015-12-09 | — | — | CN | disclosed |
| CN-102753519-B | Diacylated hydroxylamine derivatives | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-08-05 | — | — | CN | disclosed |
| US-8912342-B2 | Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines | Westfälische Wilhelms Universität Münster (DE) | 2014-12-16 | — | — | US | disclosed |
| EP-2657228-A1 | Pyrazole synthesis by the coupling of carboxylic acid derivatives and enamines | Westfälische Wilhelms-Universität Münster (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-20130204011-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | WESTFAELISCHE WILHELMS UNIVERSITAET MUENSTER (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-1100510-A2 | COMBINED PREPARATION OF ANTI-INFECTIOUSLY ACTIVE COMPOUNDS WHICH INHIBIT THE 2-C-METHYLERYTHROSE-4 METABOLIC PATHWAY, AND INHIBITORS OF LIPID METABOLISM | Jomaa, Hassan (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999066875-A2 | COMBINED PREPARATION OF ANTI-INFECTIOUSLY ACTIVE COMPOUNDS WHICH INHIBIT THE 2-C-METHYLERYTHROSE-4 METABOLIC PATHWAY, AND INHIBITORS OF LIPID METABOLISM | JOMAA HASSAN (DE) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130204011-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | PPOX, PDK2, PNPO | L3MBTL1 4685/4885ELANE 859/4885DGAT1 3922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.