Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787029 | 0.81 | ELANE (0.33) | ELANEALDH1A1DGAT1 | |
| SCHEMBL7761698 | 0.79 | L3MBTL1 (0.36) | ELANECA2DGAT1 | |
| SCHEMBL9294567 | 0.79 | ELANE (0.32) | ELANECRBNCA2DGAT1NFKB1 | |
| SCHEMBL9847018 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL19821900 | 0.77 | PKM (0.33) | KDM4E | |
| SCHEMBL10443000 | 0.76 | — | — | |
| SCHEMBL30027475 | 0.75 | ELANE (0.36) | ELANEALDH1A1DGAT1 | |
| SCHEMBL9437629 | 0.73 | PKM (0.34) | KDM4E | |
| SCHEMBL1949138 | 0.73 | DGAT1 (0.41) | CA2DGAT1 | |
| SCHEMBL28049369 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484361-A | (S) the chloro- 1- of -4- (2,5)-difluorophenyl butyl- 1- alcohol and its preparation method and application | 上海弈柯莱生物医药科技有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-1228337-C | Carbamic acid derivs. and their use as metabotropic glutamate receptor ligands | HOFFMANN LA ROCHE (CH) | 2005-11-23 | — | — | CN | disclosed |
| CN-1347406-A | Carbamic acid derivs. and their use as metabotropic glutamate receptor ligands | HOFFMANN LA ROCHE (CH) | 2002-05-01 | — | — | CN | disclosed |
| EP-0196184-B1 | ARYL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-09-16 | — | — | EP | disclosed |