Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541741 | 0.86 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL6965338 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL31434444 | 0.78 | MAPT (0.48) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL2084891 | 0.77 | TTR (0.53) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL1438861 | 0.77 | PLAU (0.53) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL28311738 | 0.75 | POLB (0.52) | ALDH1A1CYP3A4CYP1A2LMNAKMT2A | |
| SCHEMBL8539149 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL23909532 | 0.73 | TSHR (0.67) | ALDH1A1CYP3A4LMNANPSR1KDM4E | |
| SCHEMBL16289020 | 0.73 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP1A2HTR3EHTR3B | |
| SCHEMBL16093684 | 0.73 | BACE1 (0.55) | ALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447540-A | Synthetic method of primary aryl amide compounds | UNIV HUNAN | 2015-03-25 | — | — | CN | disclosed |