Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11708542 | 0.81 | KMT2A (0.68) | KMT2AKDM4EPOLBLMNASTAT3 | |
| SCHEMBL17243363 | 0.77 | HPGD (0.62) | KMT2AMMP13 | |
| SCHEMBL456749 | 0.76 | HPGD (0.57) | — | |
| SCHEMBL31281981 | 0.74 | KMT2A (0.44) | KMT2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL136440 | 0.73 | HDAC6 (0.43) | KMT2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL11711890 | 0.73 | KMT2A (0.67) | KMT2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL19259070 | 0.72 | TYMP (0.38) | KMT2AKDM4EMMP13GRIA1GRIA2 | |
| SCHEMBL2153060 | 0.72 | GRIA1 (0.60) | KMT2AALDH1A1GRIA1GRIA2GRIA4 | |
| SCHEMBL31282172 | 0.72 | KMT2A (0.49) | KMT2AMAPTKDM4EALDH1A1POLB | |
| SCHEMBL770144 | 0.72 | KMT2A (0.60) | KMT2AMAPTKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160319334-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-03 | — | — | US | disclosed |
| US-9234241-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9206477-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150038374-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-05 | — | — | US | disclosed |
| US-8624016-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8624016-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8288521-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120252700-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120252700-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120071364-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20110177975-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-7914981-B2 | identifying sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences; includes a ligation phase, a capture phase, and a detection phase; multiplex detection | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-7892747-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7893233-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7892746-B2 | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7888009-B2 | Identifying sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences; for use in disease diagnosis, food safety monitoring and forensics | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| US-7879579-B2 | Detection of preferential nucleotide sequences on solid support; generate solid support, incubate with nucleotide sequences, expose to probe, detect signal, presence of signal indicates preferential nucleotide sequences | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20100173790-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173802-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173787-A1 | DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2010-07-08 | — | — | US | disclosed |