SCHEMBL28008010

SCHEMBL28008010

CC(=O)OC1COOc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
BCHE P06276 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PKM P14618 1/20 0.34
ATM Q13315 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MTNR1A P48039 1/20 0.33
USP2 O75604 1/20 0.33
NISCH Q9Y2I1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923944 0.84 POLB (0.46) POLBGABRA1GABRB2SMN1; SMN2KMT2A
SCHEMBL3930074 0.84 POLB (0.46) POLBGABRA1GABRB2SMN1; SMN2KMT2A
SCHEMBL28818216 0.82 GAA (0.41) BCHETSHRKMT2AMEN1
SCHEMBL9785817 0.75 POLB (0.44) POLBSMN1; SMN2PKM
SCHEMBL30812977 0.75 POLB (0.44) POLBSMN1; SMN2PKM
SCHEMBL23071203 0.74 MAOA (0.32) NISCH
SCHEMBL4580637 0.74 POLB (0.42) POLBGABRA1GABRB2CYP1A2CYP2C9
SCHEMBL30403823 0.74 POLB (0.42) POLBGABRA1GABRB2CYP1A2CYP2C9
SCHEMBL9976868 0.72 POLB (0.55) POLBTSHRSMN1; SMN2PKMKMT2A
SCHEMBL1519101 0.70 ALDH1A1 (0.39) POLBCYP1A2CYP2C9TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104418771-A Preparation and application of DMAP hydrochloride as catalyst of recoverable acylation reaction UNIV NANKAI 2015-03-18 CN disclosed