Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252160 | 0.78 | HSD11B1 (0.50) | KMT2AKDM4EHSD11B1NR1I2MEN1 | |
| SCHEMBL14126507 | 0.78 | APOBEC3G (0.45) | KMT2AHSD11B1ESR1MEN1TSHR | |
| SCHEMBL11513320 | 0.75 | PTGES (0.42) | KMT2AL3MBTL1MEN1LMNATSHR | |
| SCHEMBL30038589 | 0.75 | HSD11B1 (0.49) | KMT2AHSD11B1TDP1L3MBTL1ESR1 | |
| SCHEMBL11513450 | 0.75 | APOBEC3G (0.42) | KMT2AHSD11B1MEN1TSHRSMN1; SMN2 | |
| SCHEMBL16038164 | 0.73 | TDP1 (0.45) | KMT2AKDM4ETDP1ESR1NR1I2 | |
| SCHEMBL1670976 | 0.73 | APOBEC3G (0.41) | KMT2AHSD11B1MEN1ALDH1A1 | |
| SCHEMBL10789050 | 0.73 | KMT2A (0.45) | KMT2AHSD11B1ESR1MEN1LMNA | |
| SCHEMBL11515768 | 0.73 | PTGES (0.43) | KMT2AHSD11B1L3MBTL1NR1I2MEN1 | |
| SCHEMBL11566554 | 0.71 | HSD11B1 (0.45) | KMT2AHSD11B1TDP1L3MBTL1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662007-B | Cystathionine gamma lyase (CSE) inhibitor | 索瓦制药公司 | 2018-03-16 | — | — | CN | disclosed |
| CN-104662007-A | Cystathionine-upsilon-lyase (cse) inhibitors | SOVA PHARMACEUTICALS INC | 2015-05-27 | — | — | CN | disclosed |