Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008873 | 0.82 | PTPN5 (0.35) | LTA4HCHRM5GRIN2BSLC6A4IDO1 | |
| SCHEMBL28009285 | 0.79 | CYP17A1 (0.33) | — | |
| SCHEMBL28008866 | 0.79 | LTA4H (0.46) | LTA4HSAE1UBA2IDO1SLC2A1 | |
| SCHEMBL1066850 | 0.78 | NPC1 (0.35) | CHRM5GRIN2BCA2 | |
| SCHEMBL28648372 | 0.77 | PDK2 (0.35) | — | |
| SCHEMBL28009293 | 0.75 | IDO1 (0.39) | IDO1 | |
| SCHEMBL7798036 | 0.74 | LTA4H (0.50) | LTA4HSAE1UBA2SLC6A4IDO1 | |
| SCHEMBL8124892 | 0.72 | CHRM5 (0.38) | LTA4HCHRM5GRIN2BCA2 | |
| SCHEMBL27606334 | 0.72 | LTA4H (0.47) | LTA4HSAE1UBA2IDO1SLC2A1 | |
| SCHEMBL542479 | 0.70 | LTA4H (0.63) | LTA4HSAE1UBA2SLC6A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596923-B | 1,2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer | BALTIC BIO AB | 2015-04-29 | — | — | CN | disclosed |