Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009285 | 0.81 | CYP17A1 (0.33) | DAO | |
| SCHEMBL28008873 | 0.78 | PTPN5 (0.35) | IDO1AGXT | |
| SCHEMBL899948 | 0.77 | GPR3 (0.36) | — | |
| SCHEMBL28818318 | 0.77 | TAAR1 (0.40) | IDO1AGXTTAAR1DAOMIF | |
| SCHEMBL28009292 | 0.75 | LTA4H (0.44) | IDO1 | |
| SCHEMBL3300303 | 0.73 | TAAR1 (0.60) | IDO1AGXTTAAR1DAOMAOB | |
| SCHEMBL27328871 | 0.72 | TAAR1 (0.47) | IDO1AGXTTAAR1DAOMAOB | |
| SCHEMBL28648372 | 0.72 | PDK2 (0.35) | — | |
| SCHEMBL15637648 | 0.68 | SCN10A (0.33) | — | |
| SCHEMBL1510448 | 0.68 | FFAR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596923-B | 1,2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer | BALTIC BIO AB | 2015-04-29 | — | — | CN | disclosed |