SCHEMBL28009355

SCHEMBL28009355

CNC(C(=O)NC(C)(C(N)=O)C(C)C)C(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL8741925 0.82 CTSS (0.33)
SCHEMBL27692277 0.81 CNR2 (0.31) CNR2
SCHEMBL28168000 0.76 CNR2 (0.32) CNR2
SCHEMBL9333241 0.72 CNR2 (0.33) CNR2
SCHEMBL2190101 0.72 PIK3CD (0.30)
SCHEMBL25188479 0.69 MMP1 (0.36) CNR2
SCHEMBL18492971 0.68
SCHEMBL10635153 0.67 DPP4 (0.32)
SCHEMBL892802 0.67
SCHEMBL1432498 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234517-A Bicyclic peptide ligand drug conjugates 拜斯科阿迪有限公司 2024-06-21 CN claimed
CN-118215505-A Bicyclic peptide ligand drug conjugates 拜斯科技术开发有限公司 2024-06-18 CN claimed
CN-104640842-B Aplysiatoxin-10 derivant, its preparation method and comprise its anticancer pharmaceutical composition CELLTRION INC. (KR) 2016-11-30 CN claimed
CN-104640842-A Dolastatin-10 derivative, method of producing same and anticancer drug composition containing same CELLTRION INC 2015-05-20 CN claimed
CN-118234517-A Bicyclic peptide ligand drug conjugates 拜斯科阿迪有限公司 2024-06-21 CN disclosed
CN-118215505-A Bicyclic peptide ligand drug conjugates 拜斯科技术开发有限公司 2024-06-18 CN disclosed
CN-112004826-B Reverse agonistic anti-US 28 antibodies 自由大学基金会 2024-06-14 CN disclosed
CN-113121639-B Aureostatin analogue and conjugate thereof, preparation method and application thereof 江苏恒瑞医药股份有限公司 2024-05-14 CN disclosed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN disclosed
CN-117255790-A Chemical coupling connector and application thereof 四川科伦博泰生物医药股份有限公司 2023-12-19 CN disclosed
CN-116137818-A Para-amino-benzyl linkers, methods of making and use thereof in conjugates 法国施维雅药厂 2023-05-19 CN disclosed
CN-116115771-A Materials and methods relating to linkers for use in protein drug conjugates 伊科思达医疗有限公司 2023-05-16 CN disclosed
CN-115698079-A anti-CD 79B antibody drug conjugate, preparation method and medical application thereof 上海拓界生物医药科技有限公司 2023-02-03 CN disclosed
CN-113121639-A Auristatin analogue and conjugate thereof, preparation method and application thereof 江苏恒瑞医药股份有限公司 2021-07-16 CN disclosed
CN-112004826-A Reverse agonistic anti-US 28 antibodies 自由大学基金会 2020-11-27 CN disclosed
CN-109475567-A Silanol-based therapeutic payloads 布兰克生物股份有限公司 2019-03-15 CN disclosed
CN-108778274-A With the chemotherapeutant targets neoplastic cells of coupling part and anti-protein lyase antibody conjugate by that can crack in vivo 新泽西鲁特格斯州立大学 2018-11-09 CN disclosed
CN-107073133-A Materials and methods relating to linkers for use in protein drug conjugates 吉利斯拉有限公司 2017-08-18 CN disclosed
CN-104640842-B Aplysiatoxin-10 derivant, its preparation method and comprise its anticancer pharmaceutical composition CELLTRION INC. (KR) 2016-11-30 CN disclosed
CN-104640842-A Dolastatin-10 derivative, method of producing same and anticancer drug composition containing same CELLTRION INC 2015-05-20 CN disclosed