Lithium

Lithium

SCHEMBL8741925

CN[C@H](C(=O)N[C@](C)(C(=O)O)C(C)C)C(C)C.[Li]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
ARG1 P05089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28009355 0.82 CNR2 (0.30)
SCHEMBL3206179 0.74 SLC7A5 (0.41)
SCHEMBL3206175 0.74 SLC7A5 (0.41)
SCHEMBL9159698 0.70 ALDH1A1 (0.33)
SCHEMBL5448849 0.69 ALDH1A1 (0.36)
SCHEMBL5448855 0.69 ALDH1A1 (0.36)
SCHEMBL8994793 0.69 ALDH1A1 (0.36)
SCHEMBL12175227 0.67 CA12 (0.33) CTSSCTSK
SCHEMBL19578354 0.67 CA12 (0.33) CTSSCTSK
SCHEMBL14511336 0.67 FFAR2 (0.36) ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738155-A4 MODULAR DESIGN AND SYNTHESIS OF OXAZOLONE-DERIVED MOLECULES ARQULE PARTNERS L P (US) 1997-03-19 EP disclosed
EP-0738155-A1 MODULAR DESIGN AND SYNTHESIS OF OXAZOLONE-DERIVED MOLECULES ARQULE, INC. (US) 1996-10-23 EP disclosed
WO-1995017903-A1 MODULAR DESIGN AND SYNTHESIS OF OXAZOLONE-DERIVED MOLECULES ARQULE PARTNERS, L.P. (US) 1995-07-06 WO disclosed