Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993750 | 0.83 | KDM4E (0.40) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL7982148 | 0.81 | ALDH1A1 (0.44) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL2172039 | 0.79 | KDM4E (0.41) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL4237400 | 0.76 | GABRP (0.40) | KDM4EALDH1A1CYP2A6L3MBTL1SMN1; SMN2 | |
| SCHEMBL2562397 | 0.76 | FDPS (0.37) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL6935097 | 0.76 | CCR1 (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL1943866 | 0.75 | KDM4E (0.53) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL29417023 | 0.75 | KDM4E (0.53) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL29952238 | 0.75 | KDM4E (0.43) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL7999255 | 0.75 | KDM4E (0.43) | KDM4EFDPSALDH1A1CYP2A6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104582709-A | N-alkyl 2-(disubstituted)alkynyladenosine-5-uronamides as A2A agonists | LEWIS AND CLARK PHARMACEUTICALS INC | 2015-04-29 | — | — | CN | disclosed |