Methylamine

Methylamine

SCHEMBL28010440

CC(C)(C)OC(=O)c1ccccc1-c1ccccc1.CN

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.53
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SCN1A P35498 5/20 0.48
SCN2A Q99250 5/20 0.48
SCN3A Q9NY46 5/20 0.48
SLC6A3 Q01959 4/20 0.47
SLC6A4 P31645 3/20 0.47
GRM6 O15303 1/20 0.47
ADORA3 P0DMS8 1/20 0.45
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA4 P43681 1/20 0.44
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
HNF4A P41235 1/20 0.42
ALDH1A1 P00352 2/20 0.42
SLC6A2 P23975 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9531321 0.97 BCAT2 (0.52) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL29389473 0.97 BCAT2 (0.52) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
Bromomethane SCHEMBL7011845 0.93 SLC6A3 (0.50) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL1665535 0.92 SLC6A3 (0.49) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
Alanine SCHEMBL27736021 0.90 SCN1A (0.47) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL3558536 0.86 SLC6A3 (0.48) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL8362726 0.86 GRM6 (0.47) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL517 0.85 SLC6A3 (0.50) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL6900241 0.84 SLC6A3 (0.68) BCAT2MEN1KMT2ASMN1; SMN2SCN1A
SCHEMBL9373323 0.84 SLC6A3 (0.49) BCAT2MEN1KMT2ASMN1; SMN2SCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104650217-A Exendin-4 modified by Evans blue or derivatives of Evans blue and preparation method and application of Exendin-4 UNITED WELL BIOTECHNOLOGY SHANGHAI CO LTD 2015-05-27 CN disclosed