Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 5/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389473 | 0.95 | BCAT2 (0.52) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9531321 | 0.95 | BCAT2 (0.52) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| Bromomethane SCHEMBL7011845 | 0.92 | SLC6A3 (0.50) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| Methylamine SCHEMBL28010440 | 0.92 | BCAT2 (0.53) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3558536 | 0.87 | SLC6A3 (0.48) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL517 | 0.87 | SLC6A3 (0.50) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9373323 | 0.85 | SLC6A3 (0.49) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6900241 | 0.85 | SLC6A3 (0.68) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| Alanine SCHEMBL27736021 | 0.85 | SCN1A (0.47) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8875151 | 0.84 | ACHE (0.48) | SLC6A3SLC6A4MEN1KMT2ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486043-A1 | [18 F]- LABELLED ANALOGUES OF FLUMAZENIL AS IN VIVO IMAGING AGENTS | GE Healthcare UK Limited (GB) | 2012-08-15 | — | — | EP | disclosed |
| CN-102574859-A | [18 F] - labelled analogues of flumazenil as in vivo imaging agents | GE HEALTHCARE LTD | 2012-07-11 | — | — | CN | disclosed |
| WO-2011042550-A1 | [18 F] - LABELLED ANALOGUES OF FLUMAZENIL AS IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2011-04-14 | — | — | WO | disclosed |