Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 5/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389473 | 0.87 | BCAT2 (0.52) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| SCHEMBL9531321 | 0.87 | BCAT2 (0.52) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| SCHEMBL517 | 0.86 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL1665535 | 0.85 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL6900241 | 0.84 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| Bromomethane SCHEMBL7011845 | 0.84 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| Methylamine SCHEMBL28010440 | 0.84 | BCAT2 (0.53) | SLC6A3SLC6A4SLC6A2SCN1ASCN2A | |
| SCHEMBL3558536 | 0.83 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL8875151 | 0.83 | ACHE (0.48) | SLC6A3SLC6A4SLC6A2ACHESCN1A | |
| SCHEMBL9536220 | 0.82 | SLC6A3 (0.71) | SLC6A3SLC6A4SLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078240-A1 | N-BIPHENYLMETHYLBENZIMIDAZOLE MODULATORS OF PPARG | RIPKA AMY S (US) | 2013-05-30 | — | — | WO | disclosed |
| EP-0586513-A1 | ACIDIC ARALKYL TRIAZOLE DERIVATIVES ACTIVE AS ANGIOTENSIN II ANTAGONISTS | MERCK & CO. INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5281614-A | Hypotensive agents, glaucoma or angiotensin antagonists | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1992020662-A1 | ACIDIC ARALKYL TRIAZOLE DERIVATIVES ACTIVE AS ANGIOTENSIN II ANTAGONISTS | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |