Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082476 | 0.85 | POLB (0.40) | POLBSMN1; SMN2CTSKCYP1A2CYP2C9 | |
| SCHEMBL5268183 | 0.84 | ALDH1A1 (0.40) | CTSBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27744904 | 0.84 | ALDH1A1 (0.40) | CTSBALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28198587 | 0.84 | ALOX5 (0.39) | POLBSMN1; SMN2CTSKCTSLCTSB | |
| SCHEMBL10540689 | 0.82 | MAPT (0.42) | SMN1; SMN2ALOX5HTT | |
| SCHEMBL5270550 | 0.80 | MEN1 (0.38) | CTSBALDH1A1ALOX5MEN1HTT | |
| SCHEMBL9563422 | 0.80 | MEN1 (0.38) | CTSBALDH1A1ALOX5MEN1HTT | |
| SCHEMBL8910551 | 0.79 | PTGES (0.42) | CTSKCTSLCTSBCTSHALOX5 | |
| SCHEMBL14282188 | 0.79 | CTSK (0.42) | CTSKCTSLCTSBCTSHCYP1A2 | |
| SCHEMBL5268869 | 0.79 | CSNK1E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985402-B | Tranylcypromine derivatives as inhibitors of histone demethylase LSD1 and/or LSD2 | UNIV ROMA | 2015-04-29 | — | — | CN | disclosed |