Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TSPO | P30536 | 3/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803193 | 0.87 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDTSPODNM1 | |
| SCHEMBL2801853 | 0.85 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDTSPODNM1 | |
| SCHEMBL2801687 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDTSPODNM1 | |
| SCHEMBL2800760 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDTSPODNM1 | |
| SCHEMBL13562924 | 0.83 | HPGD (0.65) | KDM4EALDH1A1HPGDDNM1NPY5R | |
| SCHEMBL16744061 | 0.83 | HPGD (0.52) | KDM4EALDH1A1HPGDTSPODNM1 | |
| SCHEMBL2800361 | 0.83 | BACE1 (0.63) | KDM4EALDH1A1HPGDDNM1BACE1 | |
| SCHEMBL29643235 | 0.83 | BACE1 (0.63) | KDM4EALDH1A1HPGDDNM1BACE1 | |
| SCHEMBL2613140 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HPGDTSPODNM1 | |
| SCHEMBL2800147 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDTSPODNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9899612-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-02-20 | — | — | US | disclosed |
| US-20140284585-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2014-09-25 | — | — | US | disclosed |
| US-8778508-B2 | Light-emitting organometallic complexes | UNIVERSAL DISPLAY CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8519130-B2 | Method for synthesis of iriduim (III) complexes with sterically demanding ligands | UNIVERSAL DISPLAY CORPORATION (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2009073246-A1 | METHOD FOR THE SYNTHESIS OF IRIDIUM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS | UNIVERSAL DISPLAY CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009073245-A1 | LIGHT-EMITTING ORGANOMETALLIC COMPLEXES | UNIVERSAL DISPLAY CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20090124805-A1 | METHOD FOR SYNTHESIS OF IRIDUIM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS | UNIVERSAL DISPLAY CORPORATION | 2009-05-14 | — | — | US | disclosed |
| US-20090108737-A1 | LIGHT-EMITTING ORGANOMETALLIC COMPLEXES | UNIVERSAL DISPLAY CORPORATION | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090108737-A1 | LIGHT-EMITTING ORGANOMETALLIC COMPLEXES | CRY1, LAGE3, CRY2 | KDM4E 1922/4885ALDH1A1 2005/4885HPGD 3835/4885 |
| US-20090124805-A1 | METHOD FOR SYNTHESIS OF IRIDUIM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS | PAICS, ITPA, MPI | KDM4E 4012/4885ALDH1A1 2362/4885HPGD 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.