Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987811 | 0.70 | MAPT (0.45) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL20610125 | 0.68 | MEN1 (0.61) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL28853261 | 0.67 | MEN1 (0.56) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL6492524 | 0.67 | KMT2A (0.64) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL3370820 | 0.67 | MEN1 (0.59) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL1893849 | 0.67 | MEN1 (0.59) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL7047429 | 0.67 | MEN1 (0.59) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL719008 | 0.66 | MAPT (0.57) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL6283244 | 0.66 | GPR84 (0.59) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL28010217 | 0.65 | SLC6A4 (0.34) | KMT2ALMNAALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447705-A | Synthesis and bioactivity evaluation of 1-indoleacetic acid-5-nitroimidazole-containing derivative thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2015-03-25 | — | — | CN | claimed |