Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | SI | P14410 | 7/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825647 | 0.79 | GPR84 (0.50) | MAPTMEN1KMT2ALMNAGPR84 | |
| SCHEMBL6689686 | 0.74 | SLC6A4 (0.51) | KMT2AGAALMNATSHRL3MBTL1 | |
| SCHEMBL28853261 | 0.71 | MEN1 (0.56) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL3370820 | 0.71 | MEN1 (0.59) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL7047429 | 0.71 | MEN1 (0.59) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL1893849 | 0.71 | MEN1 (0.59) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL28010909 | 0.70 | KMT2A (0.45) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL719008 | 0.70 | MAPT (0.57) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL6283244 | 0.70 | GPR84 (0.59) | MAPTMEN1KMT2APKMMGAM | |
| SCHEMBL11412911 | 0.69 | KMT2A (0.49) | MEN1KMT2ALMNATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283836-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | Aegera Therapeutics Inc. (CA) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001087887-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2001-11-22 | — | — | WO | disclosed |