SCHEMBL28013233

SCHEMBL28013233

Cc1ccc(SCC2(C(=O)O)CCCCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 6/20 0.42
HPGD P15428 4/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C19 P33261 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
FKBP1A P62942 1/20 0.38
RECQL P46063 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28013237 0.86 RAB9A (0.43) RAB9ANPC1ALDH1A1HPGDMEN1
SCHEMBL28013244 0.84 MTNR1A (0.43) RAB9ANPC1ALDH1A1MEN1KMT2A
SCHEMBL22046704 0.76 KMT2A (0.36) RAB9ANPC1ALDH1A1HPGDMEN1
SCHEMBL22046817 0.75 HPGD (0.35) RAB9ANPC1ALDH1A1HPGDMEN1
SCHEMBL28013838 0.73 RAB9A (0.38) RAB9ANPC1ALDH1A1HPGDMEN1
SCHEMBL13898956 0.72 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ASMN1; SMN2HTT
SCHEMBL15775551 0.72 STAT3 (0.44) ALDH1A1HPGDKMT2ACYP3A4CYP2C19
SCHEMBL28013817 0.71 MTNR1A (0.43) RAB9ANPC1ALDH1A1MEN1KMT2A
SCHEMBL8278870 0.70 CYP2C19 (0.54) ALDH1A1CYP2C19SMN1; SMN2LMNACYP1A2
SCHEMBL8280019 0.70 NPC1 (0.49) RAB9ANPC1ALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496870-A Catalytic synthesis method of sulfur-containing carboxylic acid compound and sulfur-containing amide compound UNIV HUNAN 2015-04-08 CN disclosed