SCHEMBL28013244

SCHEMBL28013244

COc1ccc(SCC2(C(=O)O)CCCCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
NPC1 O15118 2/20 0.40
TP53 P04637 1/20 0.40
RYR2 Q92736 2/20 0.40
ALDH1A1 P00352 5/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CTSK P43235 2/20 0.39
MMP1 P03956 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6627416 0.78 ITGB1 (0.47) NPC1ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL13898956 0.77 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL6626906 0.76 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2LMNAMAPTKMT2A
SCHEMBL8587309 0.75 KMT2A (0.50) NPC1ALDH1A1RAB9ASMN1; SMN2MAPT
SCHEMBL9054136 0.71 CYP1A2 (0.46)
SCHEMBL23329862 0.70 MTNR1A (0.46) MTNR1AMTNR1BNPC1TP53RYR2
SCHEMBL4255888 0.70 ALDH1A1 (0.72) MTNR1AMTNR1BNPC1TP53ALDH1A1
SCHEMBL11986376 0.70 ALDH1A1 (0.72) MTNR1AMTNR1BNPC1TP53ALDH1A1
SCHEMBL18759154 0.70 ITGB1 (0.46) NPC1ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL7310236 0.70 HSD11B1 (0.44) MTNR1AMTNR1BNPC1TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496870-A Catalytic synthesis method of sulfur-containing carboxylic acid compound and sulfur-containing amide compound UNIV HUNAN 2015-04-08 CN disclosed