Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBBP9 | O75884 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091620 | 0.83 | ALDH1A1 (0.44) | RBBP9ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27639822 | 0.83 | MAPT (0.53) | RBBP9ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Diphenylether SCHEMBL28212639 | 0.79 | RBBP9 (0.48) | RBBP9ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL22393879 | 0.79 | PLA2G4A (0.54) | RBBP9ALDH1A1RAB9APLA2G4ACES1 | |
| SCHEMBL15921297 | 0.77 | PLA2G4A (0.60) | RBBP9ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL20662531 | 0.73 | PLA2G4A (0.66) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25242978 | 0.73 | ALDH1A1 (0.57) | RBBP9ALDH1A1PLA2G4AMAPTCES1 | |
| SCHEMBL2008703 | 0.73 | PLA2G7 (0.57) | RBBP9ALDH1A1HPGDNPC1RAB9A | |
| Naphthalene SCHEMBL10946968 | 0.73 | ALDH1A1 (0.52) | RBBP9ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25243570 | 0.73 | ALDH1A1 (0.52) | RBBP9ALDH1A1PLA2G4AMAPTCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674148-A | Preparation method of (5-halogenothiazole-2-yl) benzoic acid compounds | 苏州汉德创宏生化科技有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-103442566-B | The compound of Therapeutic cancer | GTX, INC. (US) | 2015-12-09 | — | — | CN | disclosed |
| CN-102883607-B | Compounds for the treatment of cancer | GTX INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104592205-A | COMPOUNDS FOR TREATMENT OF CANCER | GTX INC | 2015-05-06 | — | — | CN | disclosed |