Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.65 |
| ▸ | KDR | P35968 | 5/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093698 | 0.89 | HDAC6 (0.67) | FLT1KDRHDAC6ALDH1A1NPC1 | |
| SCHEMBL5018962 | 0.83 | HDAC6 (0.64) | FLT1KDRHDAC6ALDH1A1NPC1 | |
| SCHEMBL28048000 | 0.80 | PDGFRB (0.61) | HDAC6ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5778943 | 0.78 | KDM4E (0.56) | HDAC6ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL1703187 | 0.78 | NPC1 (0.60) | FLT1KDRALDH1A1NPC1RAB9A | |
| SCHEMBL19616809 | 0.77 | HDAC6 (1.00) | FLT1KDRHDAC6ALDH1A1NPC1 | |
| SCHEMBL6492289 | 0.76 | INSR (0.53) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL24522599 | 0.76 | HDAC6 (0.65) | FLT1KDRHDAC6ALDH1A1NPC1 | |
| SCHEMBL19616555 | 0.76 | HDAC6 (0.72) | HDAC6ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL12895711 | 0.76 | RAB9A (0.59) | KDRHDAC6ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-104968200-A | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | WELLSTAT THERAPEUTICS CORP | 2015-10-07 | — | — | CN | disclosed |