Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093698 | 0.85 | HDAC6 (0.67) | KDM4EALDH1A1HPGDHTTNPC1 | |
| SCHEMBL28014135 | 0.78 | FLT1 (0.65) | KDM4EALDH1A1HPGDHTTNPC1 | |
| SCHEMBL5018962 | 0.77 | HDAC6 (0.64) | KDM4EALDH1A1HPGDHTTNPC1 | |
| SCHEMBL11514391 | 0.75 | FFAR1 (0.63) | HPGDLMNASMN1; SMN2HDAC6APP | |
| SCHEMBL28000617 | 0.75 | DYRK1A (0.51) | KDM4EALDH1A1HPGDLMNARAB9A | |
| SCHEMBL6692696 | 0.75 | FFAR1 (0.67) | ALDH1A1HPGDLMNARAB9AAPP | |
| SCHEMBL28048000 | 0.74 | PDGFRB (0.61) | KDM4EALDH1A1HPGDHTTNPC1 | |
| SCHEMBL3273212 | 0.74 | LMNA (0.50) | LMNASMN1; SMN2APPGAAMAPT | |
| SCHEMBL6696141 | 0.73 | HPGD (0.60) | ALDH1A1HPGDLMNAAPPMEN1 | |
| SCHEMBL6229701 | 0.73 | HPGD (0.65) | ALDH1A1HPGDLMNASMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562903-A4 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORP (US) | 2006-09-20 | — | — | EP | claimed |
| EP-1562903-A2 | MUCIN SYNTHESIS INHIBITORS | Genaera Corporation (US) | 2005-08-17 | — | — | EP | claimed |
| EP-1255544-A4 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORP (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040254096-A1 | Mucin synthesis inhibitors | GENAERA CORPORATION | 2004-12-16 | — | — | US | claimed |
| WO-2004043392-A2 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| EP-1418914-A2 | MUCIN SYNTHESIS INHIBITORS | Genaera Corporation (US) | 2004-05-19 | — | — | EP | claimed |
| US-20030236220-A1 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORPORATION (US) | 2003-12-25 | — | — | US | claimed |
| WO-2003011294-A2 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORPORATION (US) | 2003-02-13 | — | — | WO | claimed |
| EP-1255544-A1 | MUCIN SYNTHESIS INHIBITORS | MAGAININ PHARMACEUTICALS, INC. (US) | 2002-11-13 | — | — | EP | claimed |
| US-20020165244-A1 | Mucin synthesis inhibitors | GENAERA CORPORATION | 2002-11-07 | — | — | US | claimed |
| US-20020147216-A1 | Mucin synthesis inhibitors | GENAERA CORPORATION | 2002-10-10 | — | — | US | claimed |
| US-20010041685-A1 | Mucin synthesis inhibitors | GENAERA CORPORATION | 2001-11-15 | — | — | US | claimed |
| WO-2001054685-A1 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORPORATION (US) | 2001-08-02 | — | — | WO | claimed |
| US-7345051-B2 | Mucin synthesis inhibitors | GENAERA CORPORATION (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1255544-B1 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORP (US) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236220-A1 | MUCIN SYNTHESIS INHIBITORS | MUC1, CFTR, SERPINB1 | KDM4E 4561/4885ALDH1A1 1261/4885HPGD 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.