Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014355 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL2549018 | 0.75 | TDP1 (0.45) | TDP1ATMALDH1A1HTTMAPK14 | |
| SCHEMBL17786752 | 0.75 | ATM (0.62) | TDP1ATMALDH1A1HTTRAPGEF3 | |
| Ethoxycarbonyl Group SCHEMBL27744513 | 0.74 | MAPT (0.40) | TDP1ATMALDH1A1HTTMEN1 | |
| SCHEMBL28819079 | 0.74 | ALDH1A1 (0.39) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL858556 | 0.72 | PYGL (0.42) | TDP1ATMALDH1A1RAPGEF3MEN1 | |
| SCHEMBL863956 | 0.72 | TDP1 (0.42) | TDP1ATMALDH1A1HTTRAPGEF3 | |
| SCHEMBL28323325 | 0.71 | KDR (0.57) | MAPK14MEN1KMT2AMAPK13ABL1 | |
| SCHEMBL5857081 | 0.70 | TDP1 (0.51) | TDP1ATMALDH1A1HTTMEN1 | |
| SCHEMBL3491884 | 0.70 | ATM (0.55) | TDP1ATMALDH1A1HTTRAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557688-A | Synthetic method for Sorafenib intermediate and synthetic method for compound A used for synthesizing Sorafenib intermediate | ASYMCHEM LAB TIANJIN CO LTD | 2015-04-29 | — | — | CN | disclosed |