Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28015062 | 0.81 | LTA4H (0.39) | TSHRLTA4HACHEPTGS2MAOA | |
| Ethoxycarbonyl Group SCHEMBL28014279 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ELTA4HMAPTACHE | |
| Ethoxycarbonyl Group SCHEMBL28014362 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4ELTA4HMAPTACHE | |
| Ethoxycarbonyl Group SCHEMBL28014293 | 0.76 | ACHE (0.54) | TSHRALDH1A1LTA4HMAPTACHE | |
| Ethoxycarbonyl Group SCHEMBL27597884 | 0.72 | GAA (0.62) | LTA4HGAAMAPTMAOBMAOA | |
| SCHEMBL15642827 | 0.72 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4EGAAMAPT | |
| SCHEMBL13536776 | 0.70 | PARP1 (0.53) | TSHRALDH1A1KDM4EGAAMAPT | |
| Ethoxycarbonyl Group SCHEMBL27439208 | 0.70 | CYP2A6 (0.46) | ALDH1A1KDM4ELTA4HGAAMAOB | |
| Ethoxycarbonyl Group SCHEMBL27597895 | 0.70 | CYP2A6 (0.54) | ALDH1A1LTA4HGAAMAPTMAOA | |
| Ethoxycarbonyl Group SCHEMBL27613736 | 0.69 | AHR (0.62) | ALDH1A1LTA4HGAAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640853-A | Indole-amide compounds as beta-amyloid inhibitors | HOFFMANN LA ROCHE | 2015-05-20 | — | — | CN | disclosed |