Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.44 |
| ▸ | WNT3A | P56704 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28014279 | 0.99 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| Ethoxycarbonyl Group SCHEMBL28014293 | 0.89 | ACHE (0.54) | ALDH1A1MAPTHSD17B10HPGDACHE | |
| Ethoxycarbonyl Group SCHEMBL28819113 | 0.80 | MAOA (0.51) | MAPTCTNNB1WNT3ACYP2D6SLC6A2 | |
| Ethoxycarbonyl Group SCHEMBL28872615 | 0.79 | AR (0.50) | MAPTCTNNB1WNT3ACYP2D6SLC6A2 | |
| Ethoxycarbonyl Group SCHEMBL28090331 | 0.77 | MAPK14 (0.51) | ALDH1A1MAPTHSD17B10MAPK14DRD2 | |
| Ethoxycarbonyl Group SCHEMBL28014373 | 0.77 | TSHR (0.55) | ALDH1A1MAPTKDM4EACHEHTR4 | |
| Ethoxycarbonyl Group SCHEMBL27597884 | 0.73 | GAA (0.62) | MAPTLTA4H | |
| Ethoxycarbonyl Group SCHEMBL28687272 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| Ethoxycarbonyl Group SCHEMBL27439208 | 0.72 | CYP2A6 (0.46) | ALDH1A1HSD17B10KDM4EHPGDSMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL28291598 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640853-A | Indole-amide compounds as beta-amyloid inhibitors | HOFFMANN LA ROCHE | 2015-05-20 | — | — | CN | disclosed |