Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 17/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | ADAMTS13 | Q76LX8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735375 | 0.75 | ADAMTS5 (0.59) | ADAMTS5HPGDUSP2ALDH1A1LMNA | |
| SCHEMBL17295490 | 0.72 | ADAMTS5 (0.44) | ADAMTS5HPGDUSP2PIM1ALDH1A1 | |
| SCHEMBL4636824 | 0.72 | CLK1 (0.58) | ADAMTS5PIM1 | |
| SCHEMBL5140356 | 0.71 | PIK3CD (0.58) | ADAMTS5PIM1 | |
| Benzaldehyde SCHEMBL9354550 | 0.70 | GSK3A (0.60) | ADAMTS5HPGDUSP2PIM1PIM3 | |
| SCHEMBL8580941 | 0.69 | TP53 (0.45) | ADAMTS5HPGDUSP2ALDH1A1LMNA | |
| SCHEMBL8580642 | 0.68 | PTGS2 (0.57) | ALDH1A1 | |
| SCHEMBL8582453 | 0.68 | CYP1A2 (0.56) | ADAMTS5HPGDUSP2ALDH1A1LMNA | |
| SCHEMBL15281015 | 0.68 | PIM1 (0.55) | HPGDPIM1PIM3PIM2ALDH1A1 | |
| SCHEMBL2341294 | 0.68 | PIM1 (0.55) | HPGDPIM1PIM3PIM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102617564-B | Compound and preparation method thereof | UNIV XI AN JIAOTONG | 2015-04-29 | — | — | CN | claimed |
| CN-102617564-B | Compound and preparation method thereof | UNIV XI AN JIAOTONG | 2015-04-29 | — | — | CN | disclosed |