Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 14/20 | 0.59 |
| ▸ | IKBKB | O14920 | 3/20 | 0.56 |
| ▸ | RAF1 | P04049 | 3/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | AKT1 | P31749 | 3/20 | 0.56 |
| ▸ | AKT2 | P31751 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.56 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.56 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.56 |
| ▸ | PRDX1 | Q06830 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014404 | 0.75 | ADAMTS5 (0.58) | ADAMTS5ALDH1A1HPGDLMNAADAMTS13 | |
| SCHEMBL12862500 | 0.73 | MAPK1 (0.59) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL10062873 | 0.72 | MAPK1 (1.00) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL31070046 | 0.72 | MAPK1 (1.00) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL21067541 | 0.71 | MAPK1 (0.56) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL5140356 | 0.71 | PIK3CD (0.58) | ADAMTS5MAPK1MEN1NPC1MAPT | |
| SCHEMBL21460534 | 0.70 | IKBKB (1.00) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL21460535 | 0.70 | IKBKB (1.00) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL29794510 | 0.70 | IKBKB (1.00) | IKBKBRAF1RPS6KB1MAPK1AKT1 | |
| SCHEMBL8106620 | 0.70 | IKBKB (1.00) | IKBKBRAF1RPS6KB1MAPK1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2876109-A1 | FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Yuhan Corporation (KR) | 2015-05-27 | — | — | EP | disclosed |