Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010064 | 0.74 | — | — | |
| SCHEMBL1272614 | 0.72 | ALDH1A1 (0.37) | BRD4BRD2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28015182 | 0.69 | BRD4 (0.37) | BRD4BRD2L3MBTL1TP53ALDH1A1 | |
| SCHEMBL28464884 | 0.68 | TSHR (0.35) | BRD4BRD2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4189180 | 0.68 | GAA (0.44) | BRD4BRD2AKR1C3LMNAL3MBTL1 | |
| SCHEMBL761439 | 0.67 | — | — | |
| SCHEMBL767143 | 0.67 | PARL (0.30) | — | |
| SCHEMBL1877754 | 0.67 | GAA (0.43) | BRD4BRD2AKR1C3L3MBTL1ALDH1A1 | |
| SCHEMBL30203870 | 0.67 | BRD4 (0.38) | BRD4BRD2L3MBTL1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28195143 | 0.67 | TSHR (0.34) | BRD4BRD2LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619709-B | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104619709-A | Imidazopyridine derivatives as modulators of TNF activity | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |