SCHEMBL767143

SCHEMBL767143

CS(=O)(=O)NN1C(=O)CCC1=O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARL Q9H300 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1693062 0.72 MAPT (0.35)
SCHEMBL20111621 0.67
SCHEMBL28014485 0.67 BRD4 (0.35)
SCHEMBL7397314 0.67 KMT2A (0.32)
SCHEMBL64827 0.67 PARL (0.31) PARL
SCHEMBL4948829 0.66
SCHEMBL10775869 0.65 PARL (0.43) PARL
SCHEMBL15319876 0.64
Benzene SCHEMBL28164186 0.62 PARL (0.41) PARL
SCHEMBL22574843 0.62 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120071640-A1 Sulfurizing reagents and their use for oligonucleotides synthesis GIRINDUS AMERICA, INC. (US) 2012-03-22 US disclosed
EP-2382227-A1 SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS Girindus America, Inc. (US) 2011-11-02 EP disclosed
WO-2010072831-A1 SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS GIRINDUS AMERICA, INC (US) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071640-A1 Sulfurizing reagents and their use for oligonucleotides synthesis RRM1, SRRT, NSUN2 PARL 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.