Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157293 | 0.85 | TSHR (0.60) | KMT2ATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27346903 | 0.81 | KDM4E (0.45) | KMT2ATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27643364 | 0.81 | ALDH1A1 (0.44) | KMT2ATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27601611 | 0.76 | ALDH1A1 (0.47) | KMT2ATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27933040 | 0.76 | KMT2A (0.46) | KMT2AAKR1C3TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27626918 | 0.75 | AKR1C3 (0.44) | KMT2AAKR1C3ALDH1A1MAPTGAA | |
| SCHEMBL300439 | 0.74 | AKR1C3 (0.55) | KMT2AAKR1C3ALDH1A1KDM4EMAPT | |
| SCHEMBL27647064 | 0.74 | AKR1C3 (0.43) | KMT2AAKR1C3ALDH1A1MAPTGAA | |
| SCHEMBL29496654 | 0.73 | AKR1C3 (0.53) | KMT2AAKR1C3TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10854249 | 0.73 | CA2 (0.58) | KMT2AAKR1C3ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725288-A | Benzophenone hydrazone sulfonylurea compound and its preparation method and use | UNIV LANZHOU | 2015-06-24 | — | — | CN | disclosed |