SCHEMBL2801460

SCHEMBL2801460

CCSc1ccccc1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
BLM P54132 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
THRB P10828 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 5/20 0.45
TSHR P16473 2/20 0.45
HPGD P15428 4/20 0.41
HTT P42858 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
NPSR1 Q6W5P4 3/20 0.37
MAP2K7 O14733 1/20 0.36
S100A4 P26447 1/20 0.36
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
ERN1 O75460 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760109 0.84 PTGS2 (0.47) LMNABLMKMT2AMEN1THRB
SCHEMBL983464 0.81 ERN1 (0.52) LMNABLMKMT2AMEN1THRB
SCHEMBL8595709 0.81 PTGS2 (0.51) LMNABLMKMT2AMEN1THRB
SCHEMBL5405571 0.81 ALDH1A1 (0.33) LMNABLMKMT2AMEN1ALDH1A1
SCHEMBL6765848 0.80 PTGS2 (0.51) LMNABLMKMT2AMEN1THRB
SCHEMBL3682084 0.79 ALDH1A1 (0.40) LMNABLMKMT2AMEN1ALDH1A1
SCHEMBL9711982 0.79 LMNA (0.48) LMNABLMKMT2AMEN1THRB
SCHEMBL6759591 0.79 LMNA (0.43) LMNABLMKMT2AMEN1THRB
SCHEMBL9560125 0.78 PTGS2 (0.52) LMNABLMKMT2AMEN1THRB
SCHEMBL7721146 0.78 PTGS2 (0.52) LMNABLMKMT2AMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702008-B1 Method for producing 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 2001-08-29 EP claimed
EP-0572712-B1 Processes for producing 2-substituted benzo(beta)thiophene SUMITOMO SEIKA CHEMICALS (JP) 1998-01-21 EP claimed
EP-0702008-A2 Method for producing 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-03-20 EP claimed
US-5298630-A Reacting 2-alkylthiobenzaldehyde derivative with halo compound SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1994-03-29 US claimed
EP-0572712-A2 Processes for producing 2-substituted benzo(beta)thiophene SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-12-08 EP claimed
EP-3006429-B1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL CO (JP) 2019-02-06 EP disclosed
EP-2865671-B1 FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-11-01 EP disclosed
US-9718849-B2 Sulfur chelated ruthenium compounds useful as olefin metathesis catalysts BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2017-08-01 US disclosed
US-9718849-B2 Sulfur chelated ruthenium compounds useful as olefin metathesis catalysts BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2017-08-01 US disclosed
EP-2655337-B1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103261170-B Fused heterocyclic compounds and their use for pest control 住友化学株式会社 2016-08-24 CN disclosed
US-9328121-B1 Fused heterocyclic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 US disclosed
EP-0702008-B1 Method for producing 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 2001-08-29 EP disclosed
EP-1081141-A1 Method for producing 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2001-03-07 EP disclosed
US-5773626-A HALOGENATION OF A 2-(ALKYLTHIO)BENZALDEHYDE OXIME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-06-30 US disclosed
EP-0572712-B1 Processes for producing 2-substituted benzo(beta)thiophene SUMITOMO SEIKA CHEMICALS (JP) 1998-01-21 EP disclosed
US-5633384-A FROM O-ALKYLTHIOBENZONITRILES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-27 US disclosed
EP-0702008-A2 Method for producing 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-03-20 EP disclosed
US-5298630-A Reacting 2-alkylthiobenzaldehyde derivative with halo compound SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1994-03-29 US disclosed
EP-0572712-A2 Processes for producing 2-substituted benzo(beta)thiophene SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-12-08 EP disclosed