Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015755 | 0.85 | APP (0.44) | APPKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL28015179 | 0.84 | ADORA3 (0.47) | APPKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL28819119 | 0.84 | APP (0.44) | APPMGLLKDM4EGAAMGAM | |
| SCHEMBL28033960 | 0.81 | ALDH1A1 (0.51) | APPKDM4EGAAMGAMSI | |
| SCHEMBL28015721 | 0.76 | ALDH1A1 (0.45) | KDM4EGAAALDH1A1KMT2ARAB9A | |
| SCHEMBL28015197 | 0.75 | CASP3 (0.46) | APPKDM4EGAAMGAMSI | |
| SCHEMBL28015703 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL25649453 | 0.73 | KDM4E (0.44) | APPMGLLKDM4EGAAMGAM | |
| SCHEMBL3007676 | 0.73 | RAB9A (0.69) | APPMGLLKDM4EGAAMGAM | |
| SCHEMBL19057540 | 0.72 | APP (0.40) | APPMGLLKDM4EGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |