Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160548 | 0.86 | HRH3 (0.51) | HRH3PARP10MAOAHSD11B1MBTD1 | |
| SCHEMBL28160612 | 0.84 | MAOA (0.50) | HRH3PARP10MAOAHSD11B1PARP15 | |
| SCHEMBL28014793 | 0.74 | SLC6A9 (0.40) | — | |
| SCHEMBL28014792 | 0.74 | SLC6A9 (0.40) | — | |
| SCHEMBL1514836 | 0.74 | HSD11B1 (0.48) | HSD11B1L3MBTL3L3MBTL1TP53BP1 | |
| SCHEMBL27839159 | 0.73 | PARP10 (0.45) | HRH3PARP10MAOAPARP15PARP2 | |
| SCHEMBL8218040 | 0.72 | HRH3 (0.60) | HRH3PARP10MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL12128213 | 0.70 | HRH3 (1.00) | HRH3 | |
| SCHEMBL449365 | 0.70 | HRH3 (1.00) | HRH3 | |
| SCHEMBL438479 | 0.70 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482203-B | Carbocyclic GLYT1 receptor antagonists | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |