Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31272534 | 0.76 | ALPL (0.50) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31272024 | 0.73 | ALPL (0.54) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5058765 | 0.72 | — | — | |
| SCHEMBL7589708 | 0.72 | ALPL (0.50) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15552380 | 0.70 | ALPL (0.49) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL29951924 | 0.69 | ALPL (0.47) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15551589 | 0.67 | ALPL (0.49) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL1500435 | 0.66 | LMNA (0.39) | LMNACA9KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL13760175 | 0.65 | ADORA3 (0.55) | ALPLSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16509462 | 0.62 | MEN1 (0.59) | ALPLSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540831-A | Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and CNS disorders | 4SC DISCOVERY GMBH | 2015-04-22 | — | — | CN | disclosed |