SCHEMBL28015602

SCHEMBL28015602

C1C2CC3C4CC5CC(C14)C(C2)C3C5.Nc1ccc(C(=O)O)c(N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.50
ALDH1A1 P00352 9/20 0.50
TDP1 Q9NUW8 8/20 0.50
MAPT P10636 7/20 0.50
KMT2A Q03164 6/20 0.50
MEN1 O00255 5/20 0.50
CYP3A4 P08684 4/20 0.50
THRB P10828 4/20 0.50
POLB P06746 3/20 0.50
RECQL P46063 2/20 0.50
GAA P10253 2/20 0.50
USP2 O75604 1/20 0.50
PKM P14618 1/20 0.50
APEX1 P27695 1/20 0.50
BLM P54132 1/20 0.50
MCL1 Q07820 1/20 0.50
ESR2 Q92731 1/20 0.50
PTPN1 P18031 1/20 0.50
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28016139 0.86 KMT2A (0.70) KDM4EALDH1A1TDP1MAPTKMT2A
SCHEMBL715406 0.85 KDM4E (0.65) KDM4EALDH1A1TDP1MAPTKMT2A
Ammonia Solution, Strong SCHEMBL6030557 0.83 KDM4E (0.63) KDM4EALDH1A1TDP1MAPTKMT2A
SCHEMBL6030346 0.83 KDM4E (0.63) KDM4EALDH1A1TDP1MAPTKMT2A
SCHEMBL9768929 0.78 TDP1 (0.81) KDM4EALDH1A1TDP1MAPTKMT2A
Trimethylammonium SCHEMBL6742487 0.78 KDM4E (0.57) KDM4EALDH1A1TDP1MAPTKMT2A
Aminobenzoic Acid SCHEMBL3357490 0.77 KDM4E (0.55) KDM4EALDH1A1TDP1MAPTKMT2A
SCHEMBL28016134 0.72 G6PD (0.50) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL27930270 0.72 ALDH1A1 (0.50) KDM4EALDH1A1TDP1MAPTKMT2A
SCHEMBL8716259 0.72 MAPT (0.55) KDM4EALDH1A1TDP1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557472-A Adamantane derivative, preparation method and application in epoxy resin UNIV BEIJING CHEMICAL 2015-04-29 CN disclosed