SCHEMBL28016139

SCHEMBL28016139

C1C2CC3C4CC5CC(C14)C(C2)C3C5.Nc1ccc(N)c(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.70
TDP1 Q9NUW8 4/20 0.70
MAPT P10636 4/20 0.70
MEN1 O00255 4/20 0.70
THRB P10828 3/20 0.70
MCL1 Q07820 3/20 0.70
RECQL P46063 2/20 0.70
USP2 O75604 1/20 0.70
POLB P06746 1/20 0.70
PKM P14618 1/20 0.70
APEX1 P27695 1/20 0.70
BLM P54132 1/20 0.70
KDM4E B2RXH2 7/20 0.52
GFER P55789 2/20 0.52
RXFP1 Q9HBX9 1/20 0.52
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 3/20 0.50
ALOX15 P16050 3/20 0.50
HSD17B10 Q99714 3/20 0.50
HPGD P15428 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28015602 0.86 KDM4E (0.50) KMT2ATDP1MAPTMEN1THRB
SCHEMBL107833 0.85 KMT2A (0.95) KMT2ATDP1MAPTMEN1THRB
Hydrochloric Acid SCHEMBL864766 0.83 KMT2A (1.00) KMT2ATDP1MAPTMEN1THRB
SCHEMBL9768929 0.78 TDP1 (0.81) KMT2ATDP1MAPTMEN1THRB
SCHEMBL28487397 0.75 KMT2A (0.75) KMT2ATDP1MAPTMEN1THRB
SCHEMBL28016140 0.74 CDC25B (0.47) KMT2ATDP1MAPTMEN1THRB
SCHEMBL10947890 0.74 KMT2A (0.72) KMT2ATDP1MAPTMEN1THRB
SCHEMBL29091434 0.72 TDP1 (0.70) KMT2ATDP1MAPTMEN1THRB
SCHEMBL28016134 0.72 G6PD (0.50) KMT2AMAPTMEN1THRBRECQL
SCHEMBL4584345 0.72 KMT2A (0.70) KMT2ATDP1MAPTMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557472-A Adamantane derivative, preparation method and application in epoxy resin UNIV BEIJING CHEMICAL 2015-04-29 CN disclosed