Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kynuramine SCHEMBL30555814 | 1.00 | MAPT (0.50) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL28527938 | 0.88 | MAPT (0.47) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL10572853 | 0.84 | MAPT (0.52) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL7336041 | 0.83 | NR4A2 (0.55) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL4230481 | 0.83 | ALDH1A1 (0.55) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL7797864 | 0.82 | MAPT (0.46) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL16431087 | 0.82 | HDAC3 (0.53) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL30852311 | 0.82 | HDAC3 (0.53) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL5415859 | 0.80 | GAA (0.44) | MAPTGAAALDH1A1HSD17B10CFTR | |
| SCHEMBL7544320 | 0.80 | ALDH1A1 (0.47) | MAPTGAAALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| US-11987560-B2 | Inhibitors of lysine specific demethylase-1 | CELGENE QUANTICEL RESEARCH, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| EP-4286381-A2 | TREATMENT OF MERKEL CELLL CARCINOMA | Celgene Quanticel Research, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3496721-B1 | TREATMENT OF MERKEL CELLL CARCINOMA | CELGENE QUANTICEL RES INC (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-4257591-A2 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Celgene Quanticel Research, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3495349-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2023-06-28 | — | — | EP | disclosed |
| WO-2023090822-A1 | NOVEL CANNABICHROMENIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR IMPROVING COGNITIVE FUNCTION | 강원대학교 산학협력단 | 2023-05-25 | — | — | WO | disclosed |
| CN-116096715-A | Beneficial benzothiophene compositions for mental disorders or enhancement | 泰科根公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-3511319-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-3080100-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2022-11-30 | — | — | EP | disclosed |
| EP-1644316-B1 | 2-AMINOBENZOYL DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2010-03-10 | — | — | EP | disclosed |
| EP-1631548-B1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO INC (US) | 2009-10-28 | — | — | EP | disclosed |
| EP-1631548-B1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO INC (US) | 2009-10-28 | — | — | EP | disclosed |
| US-7414055-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414055-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414055-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2008-08-19 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| WO-2008041140-A2 | SUBSTITUTED ARYL-INDOLE COMPOUNDS AND THEIR KYNURENINE/KYNURAMINE-LIKE METABOLITES AS THERAPEUTIC AGENTS | NEURIM PHARMACEUTICALS (1991) LTD. (US) | 2008-04-10 | — | — | WO | disclosed |
| US-20060270673-A1 | Inhibitors of akt activity | MERCK & CO., INC. (US) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11987560-B2 | Inhibitors of lysine specific demethylase-1 | KDM1B, KDM1A, KDM3A | MAPT 3564/4885GAA 543/4885ALDH1A1 352/4885 |
| US-20060270673-A1 | Inhibitors of akt activity | AKT1, AKT2, AKT3 | MAPT 2047/4885GAA 845/4885ALDH1A1 3427/4885 |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | MAPT 643/4885GAA 67/4885ALDH1A1 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.