Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876770 | 0.84 | PNMT (0.43) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL28284898 | 0.78 | PNMT (0.43) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL16190023 | 0.78 | TDP1 (0.53) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL12227742 | 0.76 | ALDH1A1 (0.42) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL14780632 | 0.75 | MEN1 (0.43) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL13712678 | 0.75 | AKR1B1 (0.43) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL14421919 | 0.75 | PNMT (0.42) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL31561625 | 0.73 | CHRNB4 (0.44) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL27330132 | 0.73 | PNMT (0.42) | PNMTADRA2AMEN1KMT2ANPC1 | |
| SCHEMBL8039748 | 0.72 | PNMT (0.40) | PNMTADRA2AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103508961-B | Antitumor drug | CROWN BIOSCIENCE TAICANG CO LTD | 2015-07-22 | — | — | CN | disclosed |