Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231842 | 0.85 | TP53 (0.44) | TP53HSD11B1 | |
| SCHEMBL2801396 | 0.78 | ALDH1A1 (0.48) | MAPTSIGMAR1SMPD1HDAC6ALDH1A1 | |
| SCHEMBL13264322 | 0.77 | SIRT2 (0.36) | TP53RAB9ANPC1MAPK1TDP1 | |
| SCHEMBL21901591 | 0.76 | TSPO (0.46) | SMPD1HDAC6KMT2AMEN1ALDH1A1 | |
| SCHEMBL18216916 | 0.76 | RAB9A (0.50) | TP53MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL22519625 | 0.76 | NR1I3 (0.47) | TP53MAPTRAB9AMAPK1L3MBTL1 | |
| SCHEMBL21901592 | 0.75 | HSD11B1 (0.51) | MAPTALDH1A1HSD11B1LMNA | |
| SCHEMBL18705844 | 0.75 | NR1I3 (0.49) | TP53MAPTRAB9AMAPK1L3MBTL1 | |
| SCHEMBL13231784 | 0.74 | HSD11B1 (0.43) | TP53RAB9ANPC1SIGMAR1ALDH1A1 | |
| SCHEMBL17943551 | 0.74 | NR1I3 (0.48) | TP53MAPTRAB9AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| WO-2010085676-A1 | HYBRID HOST MATERIALS FOR ELECTROPHOSPHORESCENT DEVICES | UNIVERSITY OF ROCHESTER (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | SLC29A2, SLC43A3, SLC29A1 | TP53 3174/4885MAPT 218/4885RAB9A 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.