Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777994 | 0.80 | IMPDH2 (0.56) | HTR6PDE4B | |
| SCHEMBL24853984 | 0.79 | SMN1; SMN2 (0.53) | XDHPDE4B | |
| SCHEMBL30173391 | 0.79 | SMN1; SMN2 (0.53) | XDHPDE4B | |
| SCHEMBL28591150 | 0.79 | XDH (0.51) | XDH | |
| SCHEMBL30173392 | 0.79 | SMN1; SMN2 (0.53) | XDHPDE4B | |
| SCHEMBL12614442 | 0.78 | HTR6 (0.58) | HTR6PDE4BPDE4D | |
| SCHEMBL10067352 | 0.78 | HTR6 (0.58) | HTR6PDE4BPDE4D | |
| SCHEMBL2316115 | 0.77 | HTR6 (0.57) | HTR6PDE4BPDE4D | |
| SCHEMBL15970876 | 0.77 | XDH (0.49) | XDH | |
| SCHEMBL31106988 | 0.74 | IMPDH2 (0.61) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788359-A | Synthesis method of copper-promoted 3-cyano-substituted-indole compound | UNIV HUNAN | 2015-07-22 | — | — | CN | disclosed |