Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801659 | 1.00 | SLC13A5 (0.42) | SLC13A5L3MBTL1ALDH1A1PKMACSS2 | |
| SCHEMBL2798702 | 0.83 | SLC13A5 (0.42) | SLC13A5ACSS2SLC13A2SLC13A3MAPT | |
| SCHEMBL2798693 | 0.83 | SLC13A5 (0.42) | SLC13A5ACSS2SLC13A2SLC13A3MAPT | |
| SCHEMBL2826537 | 0.80 | IDH1 (0.31) | — | |
| SCHEMBL2826531 | 0.80 | IDH1 (0.31) | — | |
| SCHEMBL2799853 | 0.75 | RAB9A (0.43) | L3MBTL1ALDH1A1PKMTSHRRAB9A | |
| SCHEMBL7468653 | 0.72 | — | — | |
| SCHEMBL5509747 | 0.72 | L3MBTL1 (0.38) | SLC13A5L3MBTL1ALDH1A1PKMKDM4E | |
| SCHEMBL8625559 | 0.70 | TSHR (0.41) | L3MBTL1ALDH1A1KDM4ETSHRRAB9A | |
| SCHEMBL31563540 | 0.70 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1PKMACSS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168426-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2010-07-01 | — | — | US | claimed |
| US-20090247563-A9 | Novel Processes for the Production of Useful Intermediates | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2009-10-01 | — | — | US | claimed |
| US-20070167475-A1 | Novel Processes for the Production of Useful Intermediates | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2007-07-19 | — | — | US | claimed |
| EP-1794127-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2007-06-13 | — | — | EP | claimed |
| WO-2006033011-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2006-03-30 | — | — | WO | claimed |
| US-20100168426-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100168426-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100168426-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2010-07-01 | — | — | US | disclosed |
| US-7705155-B2 | Processes for the production of useful intermediates | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2010-04-27 | — | — | US | disclosed |
| US-7705155-B2 | Processes for the production of useful intermediates | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2010-04-27 | — | — | US | disclosed |
| US-7705155-B2 | Processes for the production of useful intermediates | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2010-04-27 | — | — | US | disclosed |
| US-20090247563-A9 | Novel Processes for the Production of Useful Intermediates | IPSEN/S.C.R.A.S. (ANDRE BOURGOUIN) (FR) | 2009-10-01 | — | — | US | disclosed |
| EP-1794127-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2007-06-13 | — | — | EP | disclosed |
| US-7135478-B2 | Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them | SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-11-14 | — | — | US | disclosed |
| WO-2006033011-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2006-03-30 | — | — | WO | disclosed |
| US-7012079-B1 | Optically pure camptothecin analogues | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-03-14 | — | — | US | disclosed |
| US-20050038064-A1 | Anticarcinogenic agents; breast, colon, lung, prostate, ovarian, and gastric cancers, leukemia, melanomas; (5R)-5-ethyl-9,10-difluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione | SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2005-02-17 | — | — | US | disclosed |
| US-6815546-B2 | ANTICANCER AGENTS | SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-11-09 | — | — | US | disclosed |
| EP-1338599-A1 | Optically pure analogues of Camptothecin | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-08-27 | — | — | EP | disclosed |
| US-20030004150-A1 | New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them | IPSEN PHARMA S.A.S. (FR) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167475-A1 | Novel Processes for the Production of Useful Intermediates | PGD, TALDO1, COASY | SLC13A5 2256/4885L3MBTL1 3140/4885ALDH1A1 449/4885 |
| US-20090247563-A9 | Novel Processes for the Production of Useful Intermediates | PGD, TALDO1, COASY | SLC13A5 2256/4885L3MBTL1 3140/4885ALDH1A1 449/4885 |
| US-20100168426-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES | PGD, TALDO1, COASY | SLC13A5 2256/4885L3MBTL1 3140/4885ALDH1A1 449/4885 |
| US-20030004150-A1 | New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them | TOP1, TOP2A, TYMP | SLC13A5 2792/4885L3MBTL1 3438/4885ALDH1A1 795/4885 |
| US-20050038064-A1 | Anticarcinogenic agents; breast, colon, lung, prostate, ovarian, and gastric cancers, leukemia, melanomas; (5R)-5-ethyl-9,10-difluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione | MCL1, BRCA1, API5 | SLC13A5 4165/4885L3MBTL1 511/4885ALDH1A1 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.