Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31534046 | 0.83 | TSHR (0.37) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL4258148 | 0.83 | TSHR (0.37) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL4258145 | 0.83 | TSHR (0.37) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL7667132 | 0.81 | TSHR (0.36) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL7667124 | 0.81 | TSHR (0.36) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL10780727 | 0.79 | GABRP (0.39) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL10780730 | 0.79 | GABRP (0.39) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL10953136 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL10953133 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL14224899 | 0.78 | LMNA (0.35) | ALDH1A1TSHRLMNAHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675355-B | Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | disclosed |