Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017381 | 0.82 | AURKB (0.40) | FAAHKCNH2TRPV1ABL1BCR | |
| SCHEMBL28155927 | 0.78 | TRPA1 (0.47) | ALDH1A1L3MBTL1TRPV1AAK1HDAC1 | |
| SCHEMBL16894189 | 0.77 | CACNA1G (0.38) | ALDH1A1L3MBTL1FAAHKCNH2TRPV1 | |
| SCHEMBL16894276 | 0.74 | AAK1 (0.36) | ALDH1A1L3MBTL1FAAHKCNH2TRPV1 | |
| SCHEMBL16965653 | 0.74 | KMT2A (0.40) | ALDH1A1FAAHKCNH2TRPV1GRIN1 | |
| SCHEMBL27619604 | 0.65 | KMT2A (0.54) | L3MBTL1TRPV1 | |
| SCHEMBL4717327 | 0.65 | ABL1 (0.57) | FAAHTRPV1ABL1BCR | |
| SCHEMBL27914450 | 0.65 | ALOX5AP (0.43) | ALDH1A1L3MBTL1KCNH2TRPV1ADORA3 | |
| SCHEMBL28242126 | 0.64 | ABL1 (0.48) | FAAHGRIN2BABL1BCRADORA3 | |
| SCHEMBL894252 | 0.64 | KMO (0.55) | FAAHTRPV1ABL1BCRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684899-B | Substituted sulfonamide compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-104684899-A | Substituted sulfonamide compounds | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |